Which ink does the Canon PIXMA TS8220 use?

The Canon PIXMA TS8220 (inkjet, 2018) uses CLI-281XXL, PGI-280XXL, CLI-281XXLPB, CLI-281, PGI-280, CLI-281PB.

Compatible cartridges

CartridgeColorYieldPagesOEM priceCost/page
CLI-281XXL black XXL670 $22.00 3.3¢ OEM · AmazonCompatible
PGI-280XXL black XXL600 $27.00 4.5¢ OEM · AmazonCompatible
CLI-281XXL cyan XXL715 $22.00 3.1¢ OEM · AmazonCompatible
CLI-281XXL magenta XXL715 $22.00 3.1¢ OEM · AmazonCompatible
CLI-281XXLPB photo-blue XXL500 $24.00 4.8¢ OEM · AmazonCompatible
CLI-281XXL yellow XXL715 $22.00 3.1¢ OEM · AmazonCompatible
CLI-281 black standard256 $13.00 5.1¢ OEM · AmazonCompatible
PGI-280 black standard200 $16.00 8.0¢ OEM · AmazonCompatible
CLI-281 cyan standard259 $13.00 5.0¢ OEM · AmazonCompatible
CLI-281 magenta standard237 $13.00 5.5¢ OEM · AmazonCompatible
CLI-281PB photo-blue standard240 $14.00 5.8¢ OEM · AmazonCompatible
CLI-281 yellow standard259 $13.00 5.0¢ OEM · AmazonCompatible

XL/high-yield cartridges usually cost more upfront but lower the cost-per-page — better if you print often.